Machine Learning and Deep Learning have been buzzwords for quite some time now, but in the last few years, the impact on real-world applications has started to show. Here, Kieran Didi discusses how AI is revolutionising protein engineering.
Chris Szeto discusses different models of T cell activation and explains why there’s a lot more to it than binding affinity. In his work just published in Nature Communications, Chris reveals the world’s first disulfide-linked T cell receptor – peptide antigen model.
The market for gene therapy in the treatment space is booming. Gene therapy products are sitting at a critical juncture: from technological pipedream to the centrepiece of clinical treatment.
The processed X-ray diffraction data used to produce the structures of SARS-Cov-2 proteins are freely available. This means that anyone can improve these models using open source software. Better structures mean more biological insights.
Like many scientific communities, structural biologists have responded extraordinarily quickly in the fight against the coronavirus (SARS-CoV-2, also referred to as 2019-nCoV) and the resultant disease COVID-19, by determining the structure of many of the viral proteins.